Holy Spirit Catholic Church was established in 1988, and is one of the largest Catholic Churches in the Sioux Falls area.
In 2022 The Sioux Falls Catholic Diocese embarked on the Set Ablaze process to aid in planning for the future of the Catholic Church in the Sioux Falls Diocese. This helps to ensure adequate priest coverage, access to the sacraments, and involvement of the laity. More information can be found at https://www.setablazesf.org/.